homehome Home chatchat Notifications


Chernobyl mutant wolves may have evolved resistance to cancer

In the radioactive exclusion zone of Chernobyl the immune systems of wild wolves have undergone striking adaptation.

Mihai Andrei
May 6, 2024 @ 7:23 pm

share Share

Artistic depiction of a wolf in the Chernobyl Exclusion Zone
Artistic depiction of a wolf in the Chernobyl Exclusion Zone. AI-generated image (Dall-E 3).

Chernobyl was one of the scariest disasters in human history. But within the radioactive ghostly expanse of the Chernobyl Exclusion Zone, nature has provided a surprising turn of events. In the past three decades since the catastrophic nuclear disaster, the abandoned landscapes have transformed into a remarkable wildlife refuge. With the humans gone, nature is healing — despite the remnant radioactivity.

In fact, as a new study shows, nature is exhibiting remarkable adaptations that could even help humans.

Mutant wolves

The Chernobyl disaster occurred on April 26, 1986, in the then-Soviet Union. It stands as one of the most catastrophic nuclear accidents in history. The explosion and fire at the Chernobyl Nuclear Power Plant released massive amounts of radioactive material into the atmosphere, spreading contamination over wide areas of Europe. The aftermath saw the evacuation of thousands from their homes in the surrounding areas, including the now-abandoned city of Pripyat. It leaves behind a haunting legacy of human displacement and suffering.

But ironically, decades later, the site and its surroundings have become a focus of scientific research and ecological recovery, offering insights into the resilience of nature and the long-term effects of radioactive contamination.

Previous studies have shown that despite the radiation, Chernobyl has become a hotspot for biodiversity. From fungus to frogs and mammals, life has found a way. Now, life is more than finding a way — it’s adapting to the new challenges.

A pack of wolves visits a scent station in the Chernobyl Exclusion Zone. The photograph was taken by one of the remote camera stations and was triggered by the wolves’ movement. Image credits: National Geographic/Jim Beasley/Sarah Webster.

Dr. Cara Love, an evolutionary biologist and ecotoxicologist at Princeton University in the US, has been studying Chernobyl’s wolves for a decade. She and her colleagues visited the exclusion zone in 2014 and placed radio collars on the wolves, tracking their movements. This not only gave the researchers an idea of the wolves’ movements — but by tracking their travels alongside radiation sensors, they could also see how much radiation the wolves were exposed to.

In addition, the researchers took blood samples to see how the wolves respond to the levels of radiation.

Overall, the researchers found that the wolves are exposed to up to 11.28 millirem of radiation every day. That’s like taking a chest X-ray every day — over 6 times the normal safe limit for humans. But what was more intriguing was how the wolves responded to radiation.

Wolf therapy

Love found that the immune systems of the wolves had adapted to change. In fact, researchers found some of the markers exhibited by cancer patients undergoing radiation treatment — suggesting that the wolves’ immune systems are taking steps to fight the radiation.

There was another striking adaptation. Some parts of the wolves’ genetic information seemed to be remarkably resilient to cancer.

In humans, researchers often look for mutations that increase cancer risk. For instance, some alterations of the BRCA1 and BRCA2 genes have been linked to an increased risk of cancer for both men and women. Although just around 1 in 400 people have this mutation, doctors need to keep an eye on it.

But Love’s work is more about looking for mutations that protect against cancer — and this is what seems to be happening with the wolves in Chernobyl.

Previous research has shown that radiation exposure can speed up genetic mutations and that some of these mutations make organisms more resistant to radiation itself. Usually, this is demonstrated in plants and simpler animals, not so much in mammals.

The signs are exciting but it’s hard to continue the research. First, the pandemic, and then Russia’s invasion of Ukraine, have made it virtually impossible for researchers to continue their work and travel to the exclusion zone.

“Our priority is for people and collaborators there to be as safe as possible.”

Hopefully, this situation will be improved soon. By unraveling the genetic mechanisms that afford Chernobyl’s wolves their resilience, scientists may uncover new strategies to enhance human resistance to radiation-induced cancers, improve the efficacy of radiation therapy, and even develop novel cancer prevention techniques.

The study was presented at the Society for Integrative and Comparative Biology’s annual meeting in Seattle and has not yet been published in a peer-reviewed journal.

This story originally appeared in February 2024 and was updated with new information.

share Share

A Dutch 17-Year-Old Forgot His Native Language After Knee Surgery and Spoke Only English Even Though He Had Never Used It Outside School

He experienced foreign language syndrome for about 24 hours, and remembered every single detail of the incident even after recovery.

Your Brain Hits a Metabolic Cliff at 43. Here’s What That Means

This is when brain aging quietly kicks in.

Scientists Just Found a Hidden Battery Life Killer and the Fix Is Shockingly Simple

A simple tweak could dramatically improve the lifespan of Li-ion batteries.

Westerners cheat AI agents while Japanese treat them with respect

Japan’s robots are redefining work, care, and education — with lessons for the world.

Scientists Turn to Smelly Frogs to Fight Superbugs: How Their Slime Might Be the Key to Our Next Antibiotics

Researchers engineer synthetic antibiotics from frog slime that kill deadly bacteria without harming humans.

This Popular Zero-Calorie Sugar Substitute May Be Making You Hungrier, Not Slimmer

Zero-calorie sweeteners might confuse the brain, especially in people with obesity

Any Kind of Exercise, At Any Age, Boosts Your Brain

Even light physical activity can sharpen memory and boost mood across all ages.

A Brain Implant Just Turned a Woman’s Thoughts Into Speech in Near Real Time

This tech restores speech in real time for people who can’t talk, using only brain signals.

Using screens in bed increases insomnia risk by 59% — but social media isn’t the worst offender

Forget blue light, the real reason screens disrupt sleep may be simpler than experts thought.

We Should Start Worrying About Space Piracy. Here's Why This Could be A Big Deal

“We are arguing that it’s already started," say experts.