homehome Home chatchat Notifications


The Bubonic Plague came from China

The bubonic plague, known to history as The Black Death or simply The Plague, was responsible for marking one of Europe’s most darkest hours, twice decimating the continent’s population, killing off two thirds. The disease is caused by a Gram-negative bacterium called Yersinia pestis, of zoonotic nature, especially carried by rodents – more exactly rats. […]

Tibi Puiu
November 1, 2010 @ 7:27 pm

share Share

A bubonic plague smear, prepared from a lymph removed from an adenopathic lymph node, or bubo, of a plague patient, demonstrates the presence of the Yersinia pestis bacteria that causes the plague. (c) Getty Images.

The bubonic plague, known to history as The Black Death or simply The Plague, was responsible for marking one of Europe’s most darkest hours, twice decimating the continent’s population, killing off two thirds. The disease is caused by a Gram-negative bacterium called Yersinia pestis, of zoonotic nature, especially carried by rodents – more exactly rats. Forget about the grim reaper, if you were living in the middle ages and saw a rat, it would have been like staring death in eyes. However, the rats wouldn’t have been the ones you needed to worry about, but the fleas who actually transmitted the plague. Practically, the infected fleas piggybacked rats until hopping off onto humans were the bacteria wreaked havoc.

The exact origins of the bubonic plague have long been discussed, most historians agreeing at a time that the disease was most probably brought from the far east via the central Asia Silk Road. This Sunday, however, an international team of medical geneticists, who studied the disease’s DNA signature, confirmed that the Black Death originated in China more than 2,600 years ago.

Scientists sequenced 17 strains of Yersinia pestis, going from mutated patogen to mutaden patogen by building a family tree. Eventually, the strains were tracked down to China, where the root of the tree is situated and all bubonic plague waves have their origins. The study, published online on Sunday by the journal Nature Genetics, was led by Mark Achtman of University College Cork in Ireland.

“The results indicate that plague appeared in China more than 2,600 years ago,” France’s Museum of Natural History, which took part in the research, stated.

“The work highlights specific mutations in the bacterium showing how the germ evolved within given geographical regions,” the museum stated in a press release. “But it demonstrates in particular that successive epidemic waves originated as a whole in Central Asia and China.”

[via NY TIMES]

share Share

Did Columbus Bring Syphilis to Europe? Ancient DNA Suggests So

A new study pinpoints the origin of the STD to South America.

Mysterious "Disease X" identified as aggressive strain of malaria

The mystery of this Disease X seems to have been solved. Now to develop an approach to handling it.

Bird Flu Strikes Again: Severe Case Confirmed in the US. Here's what you need to know

Bird flu continues to loom as a global threat. A severe case in Louisiana is the latest development in a series of concerning H5N1 outbreaks.

Scientists Discover a Surprising Side Effect of Intermittent Fasting — Slower Hair Regrowth

Fasting benefits metabolism but may hinder hair regeneration, at least in mice.

Origami-Inspired Heart Valve May Revolutionize Treatment for Toddlers

A team of researchers at UC Irvine has developed an origami-inspired heart valve that grows with toddlers.

Depression Risk Surges by 40% During Perimenopause, New Study Reveals

Women in the perimenopause stage are 40% more likely to experience depression compared to those who aren’t undergoing menopausal changes, according to a new study led by researchers at University College London (UCL). This research, published in the Journal of Affective Disorders, draws on data from over 9,000 women across the globe and underscores an […]

Scientists Call for a Global Pause on Creating “Mirror Life” Before It’s Too Late: “The threat we’re talking about is unprecedented”

Creating synthetic lifeforms is almost here, and the consequences could be devastating.

Common air pollutants (and traffic noise) linked to infertility -- both for men and for women

New research from Denmark and the US uncovers how air and noise pollution disrupt fertility, from impairing sperm and egg quality to reducing IVF success rates.

New 3D Bio-printer Injects Living Cells Directly Onto Injuries To Heal Bones and Cartilage

In recent years, 3D printing has evolved dramatically. Once limited to materials like plastic or resin, it now extends to human cells, enabling the creation of living tissues. However, bioprinting remains a slow and limited process—until now. This latest innovation promises to change that. A team of researchers has introduced a new, cutting-edge bioprinting system […]

9,000-year-old non-stick trays was used to make Neolithic focaccia

Husking trays not only baked bread but also fostered human connection across an area spanning 2,000 km (~1,243 miles)